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The team is shocked when Leo Dalton's wife and daughter are killed when a fancy sports car careens out of control and smashes into a café. The police are puzzled by the cause of the crash but believe the driver may have been involved in a identity theft ring when they find several several passports and ID cards in the vehicle. Meanwhile, Nikki must perform urgent autopsies on two bodies found floating in the river.
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正在休假的警察Darren（郭富城）与好友兼搭档Alex（王力宏）一起出席后者女友的时装发布会时，目睹一桩谋杀案，两人立刻停止休假投入到了破案中。调查时，两人发现案件异常复杂，牵涉到大陆南方某城的一个庞大的犯罪组织，赶赴到该城后，两人结识为调查一宗涉及国际犯罪组织的案件而深入虎穴当卧底的国际刑警Norika（藤原纪香）。 为引出大鱼，Norika铤而走险假扮模特儿走秀，Darren与Alex则在暗中观察，当等来目标人物与之发生枪战时，Alex不幸中弹身亡。伤心至极的Darren发誓要将黑帮铲除，他和Norika也渐渐生出感情。
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保罗·吉亚马提（Paul Giamatti 饰）是纽约一个剧团的演员，他正在排演契诃夫的戏剧《万尼亚舅舅》。但是这出戏让他身心疲惫，几近崩溃。偶然机会，保罗找到一家名为灵魂仓库的机构。利用先进的技术，保罗成功地将自己95%的灵魂提取出来。在此之后，他的演技没有任何进展，反而常常感到莫名的空虚，并且性格也发生变化。为了回归正常生活，保罗在医生的建议下“安装”了一个俄罗斯女人的灵魂，但却让他更加烦躁。他强烈建议要回属于自己的灵魂，却发现原本妥善保存的灵魂已经不翼而飞…… 本片荣获2009年捷克卡罗维发利国际电影节最佳男主角奖（Paul Giamatti）。
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The pathologists investigate when a military helicopter crashes into a refugee detention center. Harry and Nikki actually witnessed the crash and were first on the scene but the case is complex since the center was Ministry of Defense property leased to the Home Office. The team is shocked at the conditions they find in the center and Harry, who has a close friend in the RAF, is shaken when a government Minister attributes the accident to pilot error.
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雷米（玛勒姆·帕坎 Maleaume Paquin 饰）自幼就失去了父母沦为孤儿，10岁那一年，贪婪的养父为了一点点的蝇头小利将雷米卖给了街头艺人维塔利斯（丹尼尔·奥图 Daniel Auteuil 饰），就这样，年幼的雷米开始了和维塔利斯，以及他的马戏团一起的流浪演艺生涯。 幸运的是，维塔利斯是一个善良的男人，他非常同情雷米不幸的遭遇，不仅供他吃穿住宿，还教会了他念书识字。一次偶然中，维塔利斯在雷米的身上发现了极高的唱歌天赋，于是他悉心培养，想要保护并发扬雷米这份脆弱的天赋。随着年龄的增长，雷米逐渐开始对自己的过去产生了好奇心，内心里流淌的一首神秘的摇篮曲成为了牵引雷米找回过往的重要线索。
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Following a court appearance for drunk driving, Leo is required to perform unpaid work as a punishment, assisting AJ, a community worker on a run-down,largely black-occupied housing estate in South London. AJ is hoping to divert boys away from crime by encouraging them to do sports, and, though initially dismissive of Leo as a white intruder, comes to respect him after he has saved the life of Errol, a former gang member now anxious to keep his little brother Levi out of trouble. Errol has been stabbed in the leg by members of a gang from a rival estate and Leo stops him from bleeding to death. Earlier in the week a young girl called Shana Block was stabbed to death at a funfair and her murder recorded on a mobile phone. As Shana lived on the estate police sergeant Wallace involves Leo as a go-between with the suspicious residents. Also on the scene are Harry and Nikki, the latter dating Ryan, a young Scottish paramedic she met when called to the scene of Shana's death.
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As Leo's replacement Thomas Chamberlain arrives Nikki investigates the murders of Rachel Freedman, shot in the head, and her little autistic son Nathan, who was poisoned. Nikki rejects policewoman Anne Burchett's theory that Rachel killed them both but is perturbed when an impostor, claiming to be Rachel's sister, visits the morgue. At the same time the disfigured corpse of Eva Liron is discovered, killed with the same poison as Nathan. She had been the nanny to French hot shot footballer Isaac Dreyfus and was planning to blackmail him over a sex tape of them both. Jewish Isaac is a controversial figure due to his anti-Muslim sentiments but he denies ant part in the murders. Then another victim, Isaac's agent Mousa, is discovered dead.
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This year Silent Witness celebrates its 20th anniversary with five explosive stories that take the show into new and uncharted territories as well as delving into the murky depths of city life. Five contemporary thrillers that start amongst the familiar landscapes of London and end up in the dusty scrubland of Mexico.